Technologies Available for License : Biotechnology
DNA Libraries
Tech ID: 04-94-60
Technology Description:
Methods for making chromosome-specific libraries from single chromosomes are disclosed in which a single flow-sorted chromosome (or subchromosomal fragment) is efficiently collected, and DNA extracted from the chromosome is amplified, e.g., by PCR. After they are produced, the resulting libraries are screened, e.g., by in situ hybridization or hybridization to a chromosome spot blot, to identify libraries that arise from the chromosome (or subchromosomal fragment) of interest. The single-chromosome amplification libraries and individual DNA sequences from the libraries are useful, for example, for cytogenetic analysis and cancer diagnostics.
Application:
Technology Offer:
The Washington Research Foundation is seeking commercial partners to develop
therapeutics based on the technology. License or option arrangements are
negotiable. US rights to the technology are available.
Patents/Publications:
Patents covering this technology include United States Patent No. 5814444
which issued in September 1998.,
For additional information, please contact:
Beth G. Etscheid, Ph.D.
Director of Licensing
Washington Research Foundation
2815 Eastlake Avenue E, Suite 300
Seattle, WA 98102
Tel: 206.336.5600
Fax: 206.336.5615
betschei@wrfseattle.org